MINIATURIZED SHAKE-FLASK HPLC METHOD FOR DETERMINATION OF DISTRIBUTION COEFFICIENT OF DRUGS USED IN INFLAMMATORY BOWEL DISEASES

Miniaturized shake-flask HPLC method for determination of distribution coefficient of drugs used in inflammatory bowel diseases

A new method for determination of distribution coefficient of drugs azathioprine, 6-mercaptopurine and 6-thioguanine and nutrient folic acid used in the treatment of inflammatory bowel disease based on a miniaturized shake-flask and HPLC/DAD was developed.Special attention was made to the most commonly reported problems in the measurement of distri

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Impact of the implementation of carbon emission trading on corporate financial performance: Evidence from listed companies in China.

With the development of ecological paradigm coupled with the relentless implementation of myriad environmental policies in China, the rapid development of carbon emission trading and carbon trading market has had a vital impact on the financial performance of enterprises at the microlevel.This study has sampled the A-share listed companies in China

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Large hiatus hernia: time for a paradigm shift?

Abstract Background Laparoscopic large hiatal hernia (LHH) repair remains a challenge despite three decades of ongoing attempts at improving surgical outcome.Its rarity and complexity, coupled with suboptimal initial approach that is usually best suited for small symptomatic herniae have contributed to unacceptable higher failure rates.Results We h

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